Acyl Halides
Medchemexpress LLC Umeclidinium (bromide) | 869113-09-7 | 508.49 | 5 G
Umeclidinium bromide is a novel muscarinic acetylcholine receptor (mAChR) antagonist. It exhibits high affinity for human M1-M5 mAChRs, with Ki values ranging from 0.05 to 0.16 nM. This compound demonstrates antagonist activity at the human cloned muscarinic M3 receptor and inhibits the human ether-a-go-go-related gene (hERG) channel tail current.
- Targets mAChR1 and mAChR5.
- Inhibits acetylcholine-induced calcium mobilization in CHO cells.
- Demonstrates slow functional reversibility at M3 mAChRs.
- Inhibits human ether-a-go-go-related gene channel tail current.
Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 5 G
1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis, among other processes.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Useful for cancer research
Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | MFCD00149575 | >98.0% | 373.4 g/mol | C17H19N5O5 | 5 G
N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analog of deoxyadenosine bearing an N6-benzoyl protecting group. It is provided as a monohydrate solid for research use (CAS 305808-19-9) with purity ≥98.0%, and is used as an intermediate in nucleoside chemistry, oligonucleotide synthesis, and studies of nucleoside analog activity.
- High purity suitable for research applications.
- Monohydrate solid form for stable handling and storage.
- Serves as an intermediate in nucleoside and oligonucleotide synthesis.
- Compatible with standard analytical and synthetic workflows.
- Supplied in small-scale laboratory pack sizes for bench use.
Medchemexpress LLC Oleyl bromide ((Z)-1-Bromooctadec-9-ene) | 6110-53-8 | 98.4% | 331.37 | 25 MG
Oleyl bromide is a hydrophobic compound that can carry out ring-opening reaction through a process called 'encapsulation.' It can also be used as the starting material in the synthesis of oleylphosphonates.
- Hydrophobic compound
- Can carry out ring-opening reactions
- Used as starting material in synthesis of oleylphosphonates
- For research use only
- Biochemical assay reagent
Medchemexpress LLC Tiotropium bromide | 136310-93-5 | 472.42 | 1 ML
Tiotropium bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. It is a 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. It improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
- Targets mAChR
- Involved in GPCR/G Protein and neuronal signaling pathways
- Long-acting, stops signaling between neurons and leads to muscle relaxation
- Used in the management of chronic obstructive pulmonary disease
- Improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
Cayman Chemical N4-benzoyl-CytIdIn 250g
A benzyolated derivative of cytidine; a substrate of UCK1 and UCK2; has been used in the synthesis of 2ʹ-OH protecting groups for solid-phase RNA synthesis and synthetic oligonucleotides for UV light-induced and targeted gene silencing in zebrafish embryos
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 508.49 | 250 MG
Umeclidinium bromide is a novel mAChR antagonist with high affinity for cloned human M1-M5 mAChRs. It exhibits slow functional reversibility at cloned human M3 mAChRs and at endogenous mAChR in isolated human bronchus. It also inhibits the human ether-a-go-go-related gene channel tail current in human embryonic kidney 293 cells.
- Target: mAChR
- Pathway: GPCR/G protein, neuronal signaling
- Inhibits human ether-a-go-go-related gene channel tail current
- Demonstrates slow functional reversibility at M3 mAChRs
Medchemexpress LLC Cetrimonium bromide | 57-09-0 | MFCD00011772 | 98.0% | 25 MG
Cetrimonium bromide (CTAB) is a quaternary ammonium and an orally active cationic surfactant. It exhibits toxicity and has an anticancer effect. This compound inhibits cell migration and invasion by modulating both canonical and non-canonical TGF-β signaling pathways and can also be utilized for DNA extraction.
- Cationic surfactant
- Exhibits toxicity and anticancer effect
- Inhibits cell migration and invasion
- Modulates TGF-β signaling pathways
- Can be utilized for DNA extraction
Medchemexpress LLC Umeclidinium (bromide) | 869113-09-7 | 508.49 | 500 MG
Umeclidinium bromide is a novel mAChR antagonist with high affinity (Ki) for cloned human M1-M5 mAChRs, ranging from 0.05 to 0.16 nM. It is intended for research use only and not for patient use.
- Inhibits the human ether-a-go-go-related gene channel tail current in human embryonic kidney 293 cells (IC50=9.4 μM).
- Potent agent demonstrating slow functional reversibility at cloned human M3 mAChRs and at endogenous mAChR in isolated human bronchus.
- Utilized in ligand binding assays with [3H]-N-methyl scopolamine for mAChR characterization.
- Applicable for in vitro studies and in vivo experiments in mice.
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 100 MG
Pinaverium bromide is an L-type calcium channel blocker that selectively targets the gastrointestinal tract. It is effective in relieving pain, diarrhea, and intestinal discomfort, offering therapeutic benefits without significant adverse effects in patients with Irritable Bowel Syndrome (IBS). It is intended for research use only.
- Selectively blocks L-type calcium channels
- Relieves pain, diarrhea, and intestinal discomfort
- Provides therapeutic efficacy for Irritable Bowel Syndrome (IBS)
- Exhibits good safety profile with no significant adverse effects
- Inhibits neutrophil migration and ROS production
- Reduces expression of inflammatory cytokines (IL-1β, IL-6, TNF-α)
- Increases survival rate and reduces lung and liver injury in LPS-induced animal models
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 50 MG
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
- Long-acting, 24-hour, anticholinergic bronchodilator
- Used in the management of chronic obstructive pulmonary disease
- Improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure
- Stops signaling between neurons and leads to muscle relaxation
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 10MM 1ML
Fentonium bromide | 5868-06-4 | 98.8% | 10MM 1ML
![eMolecules 7699-45-8 | Zinc bromide | Oakwood Chemicals | MFCD00011294 | 225.190 | Br2Zn | 98.000 | [Zn++].[Br-].[Br-] | 5g | 480169581](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000164649.jpg-250.jpg)
eMolecules 7699-45-8 | Zinc bromide | Oakwood Chemicals | MFCD00011294 | 225.190 | Br2Zn | 98.000 | [Zn++].[Br-].[Br-] | 5g | 480169581
Zinc bromide | Oakwood Chemicals | 7699-45-8 | MFCD00011294 | 225.190 | Br2Zn | 98.000 | [Zn++].[Br-].[Br-] | 5g | 480169581
![eMolecules 7789-45-9 | Copper(II) bromide | Chem-Impex | MFCD00010970 | 223.354 | Br2Cu | 99.000 | [Cu++].[Br-].[Br-] | 250g | 272388350](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492578.jpg-250.jpg)
eMolecules 7789-45-9 | Copper(II) bromide | Chem-Impex | MFCD00010970 | 223.354 | Br2Cu | 99.000 | [Cu++].[Br-].[Br-] | 250g | 272388350
Copper(II) bromide | Chem-Impex | 7789-45-9 | MFCD00010970 | 223.354 | Br2Cu | 99.000 | [Cu++].[Br-].[Br-] | 250g | 272388350
TARGETMOL CHEMICALS INC KRN2 BROMIDE 5MG
Also available in 2mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. KRN2 bromide is a potent selective inhibitor of nuclear factor of activated T cells (NFAT5 IC50= 0.1 μM). purity: 99%